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Submit scientific paper, scientific publications, International Research Journal | Meždunarodnyj naučno-issledovatel’skij žurnal

ISSN 2227-6017 (ONLINE), ISSN 2303-9868 (PRINT), DOI: 10.18454/IRJ.2227-6017
ПИ № ФС 77 - 51217

Featured articles

POSSIBILITIES OF SURGICAL TREATMENT OF METASTATIC LESIONS OF SPINE

Posted in 2018, Issue №6(72) June 2018, MEDICINE | 0 comments

The article presents various options for surgical treatment of metastatic spine lesions. The material presented is the study of a number of domestic and foreign scientific articles, for the period of 2000 to 2017. Operative treatment of metastatic spinal lesions in most cases is palliative, aimed at restoring the neurological deficit, reducing the pain syndrome, implementing local control over tumor growth, restoring stability in the affected segment.

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MULTIOCULAR SCLEROSIS. COMPARISON OF INCIDENCE RATE IN OMUTNINSKIY (NORTHERN) AND URZHUMSKIY (SOUTHERN) DISTRICTS OF THE KIROV REGION

Posted in 2018, Issue №6(72) June 2018, MEDICINE | 0 comments

The main theories of the etiology and pathogenesis of multiocular sclerosis are presented. The main symptoms are considered, the types of the course of the disease are given. The level of occurrence of multiple sclerosis in men and women was compared in the study. Attention is paid to the age characteristic of the debut of multiocular sclerosis. The main objective of the paper is to assess the impact of the geographical factor on the risk of multiocular sclerosis by comparing the incidence of the disease in Omutninskiy District (Northern) and Urzhumskiy District (Southern) of the Kirov Region.

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MODERN VIEWS ON THE PATHOGENETIC THERAPY OF ERYSIPELAS

Posted in 2018, Issue №6(72) June 2018, MEDICINE | 0 comments

Present-day data on the incidence of erysipelas and factors predisposing to its development are presented in the paper. Current directions for studying the pathogenesis of the disease are presented, as well as an overview of the main methods of pathogenetic therapy of erysipelas and prevention of its relapse. The relevance of the use of drugs that have an immunomodulating effect on the factors of innate immunity is shown. The necessity of using pathogenetic therapy, which simulates the activity of macrophagal phagocytosis, in the complex therapy of erysipelas of the lower extremities is substantiated.

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USAGE OF SOLID-PHASE EXTRACTION METHOD FOR PURIFICATION OF 16-α[18F]FLUORINE-17β-ESTRADIOL, A RADIOTRACER FOR PET DIAGNOSTICS OF BREAST CANCER

Posted in 2018, CHEMISTRY, Issue №6(72) June 2018 | 0 comments

A new method of solid-phase extraction (SPE) for the purification of 16α-[18F]fluorine-17β-estradiol ([18F]FES), radiopharmaceutical (RPC) for PET diagnostics of estrogen-positive (ER +) breast cancer is proposed. [18F]FES was obtained by nucleophilic radiofluorination of the cyclic sulfanyl precursor MMSE with subsequent deprotection by hydrolysis in an acidic medium. In order to separate [18F]FES from the reaction mixture by SPE method, disposable cartridges based on various sorbents have been studied. It was shown that the use of the OASIS WAX 3cc cartridge is the most effective and allows to obtain [18F]FES with radiochemical purity > 99% and the residual content of MMSE and chemical impurities of 2-5 μg/ml, which allows using this RPC in preclinical and clinical studies. The content of ethanol in the injection form of the drug is 5%, which meets the requirements of the State Pharmacopoeia. The advantage of the new cleaning method is simplicity, speed (40 min) and the possibility of automation in modern synthesis modules. The use of disposable SPE cartridges at the purification stage meets modern GMP requirements.

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ASSESSMENT OF SUSTAINABILITY OF AGRICULTURAL PRODUCTION IN REGION ON BASIS OF FIVE-LEVELS FUZZY [0,1]-CLASSIFIERS

Posted in 2018, ECONOMICS, Issue №6(72) June 2018 | 0 comments

This study aims to develop a methodology for assessing the sustainability of agricultural production in the region on the basis of factors of two groups: economic and environmental. The objective of the study is to develop methods that allow the formation of a comprehensive assessment of the sustainability of agricultural production in the region on the basis of standard multilevel fuzzy [0,1] – classifiers by aggregating estimates on a set of heterogeneous indicators. Aggregation is performed on the basis of time series of numerical values of heterogeneous indicators, reflecting both the level and the growth rates of indicators for the periods under study; it allows not only to give numerical estimates of the intensity of agricultural production and the degree of its impact on the ecology of the region, but also to indicate the most problematic areas of development of the agro-industrial complex of the region, and also to rank the regions on the basis of the estimates constructed.

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TRANSLATION OF PHRASEOLOGICAL UNITS AS MEANS TO REALIZE PRAGMATIC POTENTIAL OF ENGLISH POLITICAL MASS MEDIA DISCOURSE

Posted in 2018, Issue №6(72) June 2018, PHILOLOGY | 0 comments

At the present time news concerning political events and politicians are really ubiquitous. In order to make political mass media discourse more bright and impressive, politicians and journalists use different expressive and figurative linguistic units, with phraseological units being among them. Translators for their part face the problems of transferring them appropriately so that to preserve the pragmatic potential of original mass media texts and to influence the target audience.

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USAGE OF HASHTAGS IN INSTAGRAM-BLOGS

Posted in 2018, Issue №6(72) June 2018, PHILOLOGY | 0 comments

The Research article presents the analysis of the features of the hashtag operation in Instagram-blogs. The possibility of expressing hashtags with grammatical means of different levels is noted. The versions of hashtags are shown, as well as the forms of their implementation in posts of the Instagram-blog. Features of the hashtag-heading are considered. Trend, brand and content characterize hashtags. The hashtag is designated as a special element of hypertext, which has a certain communicative status, depending on the intentions of the author.

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SOME ANCIENT ETHNOTONICS OF MANGISTAUS REGION

Posted in 2018, Issue №6(72) June 2018, PHILOLOGY | 0 comments

This Research article presents the problem of some ancient ethnotoponyms of the Mangistau region, which the author describes as a “cultural code of the nation.” The aim of the work is to analyze the study of Kazakh ethnonyms through the ancient ethnotoponyms of the named region. The main attention in the work is focused on the views of domestic and foreign scientists on the ancient ethnotoponyms of the region, the use of methods of historical and linguistic analysis, it is proposed to continue their study about the “cultural code of the nation.” The work is interdisciplinary in character, written at the junction of “history-geography-linguistics” and is important for the interpretation of ancient ethnotoponyms. The author seeks to follow the process of analyzing the historical and linguistic aspect of regional ethnotoponyms in order to form the patriotic spirit of modern youth; considerable attention is paid to the issue of “new Kazakhstani patriotism”.

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NEW FORMATS OF DIGITAL JOURNALISM OF RUSSIAN REGION (ON EXAMPLE OF REPUBLIC OF TATARSTAN)

Posted in 2018, Issue №6(72) June 2018, PHILOLOGY | 0 comments

New formats of modern media activities in the context of digital journalism development are explored in this work. Particular focus is on the Internet media that are used in a multi-ethnic region to fully present information, conduct interactive interaction with the audience and other participants in the communication process, providing a full-fledged representation of public and media interests. The means of social interaction of Internet media are defined, including permanent representation in the virtual environment of traditional media content and monitoring of audience activity. The structural and typological features of this format of digital journalism are revealed, including management of the Internet media; social and commercial interaction; identification by the audience and partners; a permanent address on the Internet and links via hyperlinks.

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PHRASEOLOGICAL UNITS in NOVE OF ERILIK ERISTEEN “KARIES TUOLUUTA” (WELFARE EXECUTION)

Posted in 2018, Issue №6(72) June 2018, PHILOLOGY | 0 comments

The Research article is devoted to the peculiarities of the functioning of phraseological units (PU) of the Yakut language in the story “Karies tuoluuta” by famous Yakut writer, Erilik Eristeen (Semen Stepanovich Yakovlev), was behind the formation of the Yakut language. The phraseology of the texts of Erilik Eristeen was not previously investigated. 281 FEs were selected with the continuous sampling, method. Observations show that in most cases the author of the story uses commonly used phraseological units. Particular attention is paid to the use of the writer variants and occasional phraseological units. Expression-stylistic functions of phraseological units are revealed.

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