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ВЛИЯНИЕ БЕЛОЙ НАФТАЛАНОВОЙ НЕФТИ НА ДИНАМИКУ УРОВНЯ ПРОДУКТОВ ПЕРЕКИСНОГО ОКИСЛЕНИЯ ЛИПИДОВ

Table 1 - Dynamics of changes in LPO products in the blood of rats under experimental osteoarthritis conditions following treatment with Naftalan oil, White Naftalan oil, and Artra ointment

Treatment

Effect – Lipid Peroxidation Products (HP – relative units, MDA – nmol/mg protein)

Day 10

Day 15

Day 20

Day 25

HP

MDA

HP

MDA

HP

MDA

HP

MDA

Intact (healthy control group)

1.80 ± 0.02

1.70 ± 0.02

1.80 ± 0.04

1.70 ± 0.02

1.80 ± 0.03

1.70 ± 0.03

1.80 ± 0.02

1.70 ± 0.03

Osteoarthritis, %

2.25±0.02a

25

1.92 ±0.02c

12.9

2.45±0.01d

36.1

2.00±0.04b

17.6

2.67±0.02b

48.3

2.40±0.03c

41.2

2.73±0.02a

51.7

2.54±0.02b

49.4

Osteoarthritis +Naftalan oil, %

2.00±0.03b

11.1

1.62±0.02d

-4.7

1.88±0.02a

4.4

1.72±0.02c

1.2

1.83±0.03d

1.7

1.79±0.02b

5.3

1.80±0.03c

0

1.74±0.03d

2.4

OA + White Naftalan oil, %

2.18±0.02d

21.1

1.73±0.03b

1.8

1.95±0.03a

8.3

1.74±0.02b

2.4

1.86±0.03c

3.3

1.77±0.02c

4.1

1.84±0.02a

2.2

1.79±0.02b

5.3

OA + Artra ointment, %

2.10±0.02d

16.7

1.83±0.02b

7.6

1.85±0.02a

2.8

1.74±0.03b

2.4

1.81±0.02c

0.6

1.73±0.02c

1.8

1.80±0.02a

0

1.72±0.02b

1.2

HP – relative units; MDA – nmol/mg protein; M ± m; n = 10