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THE EFFECT OF STEROID HORMONES ON PHYSIOLOGICAL PARAMETERS AND HUMAN BODY COMPOSITION DURING SHORT-TERM SIMULATION OF SPACE FLIGHT FACTORS

Table 1 - Body composition, physiological and hormonal parameters of test-subjects in dry immersion

Parameter, units of measurement

Background

Dry immersion

Body mass,  kg

72,7±3,8

70,8±2,6

Body mass, %

100±0

97,4±0,3*

Body mass index, kg/m2

23,3±1,1

22,4±0,7

Body mass index,  %

100±0

96,0±0,4*

Body surface area, m2

1,89±0,05

1,87±0,04

Body temperature, oC

36,3±0,1

36,1±0,1

APs, mm Hg

116±2

110±1*

APd, mm Hg

72±2

70±2

Heart rate, beats/minute

67±3

61±2

Cardiac output, L/minute

4,8±0,2

4,2±0,2*

Specific REE, MJ/m2/day

3,8±0,01

3,8±0,01

Water intake, ml/day

2538±216

2173±181*

Diuresis, ml/day

2027±213

1843±219

Partial water balance, ml/day

511±128

330±99

Protein, g/L

71,1±0,8

71,7±0,6

Albumin, g/L

43,9±0,5

44,5±0,4

Globulins, g/L

27,3±0,9

27,2±0,7

Progesterone, nmol/L

0,7±0,1

1,1±0,1

Progesterone, %

100±0

166±19*

Cortisol, nmol/L

469±26

536±26

Cortisol, %

100±0

116±6*

Free cortisol, nmol/L

90,1±13,2

120,9±4,4

Testosterone, nmol/L

20,6±0,7

23,5±0,9

Testosterone, %

100±0

114±4*

Free testosterone, pmol/L

106±23

120±21

Aldosterone, pmol/L

450±14

490±10*

Aldosterone, %

100±0

114±4*

Estradiol, pmol/L

176±11

191±27

* - significant difference with background (p <0,05); APs – arterial pressure systolic; APd – arterial pressure diastolic; REE – rest energy expenditure; VО2 – oxygen demand; n=10; Mean±S.E.M