Parameter, units of measurement

N=8

Isolation (n=12)

Placebo

HGMF

PHE-

PHE+

Body mass,  kg

78,7±3,6

78,4±3,7

68,2±7,2

68,1±5,0

Body mass index, kg/m2

24,2±1,0

24,1±1,1

23,9±1,9

22,4±1,1

APs, mm Hg

117±4

117±2

–

–

APd, mm Hg

71±2

71±2

–

–

Heart rate, beats/minute

58±3

57±3

–

–

Cardiac output, L/minute

4,4±0,3

4,3±0,2

–

–

Extracellular fluid, L

20,4±0,9

20,8±0,9

17,9±1,7

18,2±1,4

Extracellular fluid, % to background

100±2

102±3

100±1

103±1

Cellular fluid, L

25,9±1,1

26,2±1,0

24,9±2,1

22,6±1,6

Cellular fluid, % to background

102±2

104±2

98±1

101±1*

Lean body mass, kg

63,3±2,6

64,2±2,6

58,4±5,2

55,8±4,0

Lean body mass, % to background

101±1

103±2

99±1

102±1*

Body cell mass, kg

38,9±1,5

39,4±1,3

30,3±2,2

35,8±1,7

Body cell mass, % to background

106±4

108±4

100±1

101±1

Intracellular substance, kg

24,4±1,3

24,9±1,5

28,1±3,1

20,0±2,3

Intracellular substance, % to background

96±5

97±4

97±1

104±1*

Dry lean body mass, kg

17,0±0,7

17,2±0,7

15,7±1,4

15,0±1,1

Dry lean body mass, % to background

101±1

103±2

99±1

102±1*

REE, MJ/m2/day

4,0±0,1

4,0±0,1

4,2±0,3

4,0±0,2

Resting VО2, L/minute

0,26±0,02

0,27±0,01

–

–

Respiratory coefficient

0,92±0,05

0,89±0,04

–

–

Cortisol, nmol/L

149±15

167±52

369±51

467±29

Cortisol in saliva, nmol/L

70,1±5,5

93,9±20,8

–

–

Aldosterone, pmol/L

141±36

187±42

968±159

801±94

Aldosterone, % to background

103±30

129±38

138±17

89±2*

Testosterone, nmol/L

–

–

12,1±3,6

9,1±3,4

Testosterone, % to background

–

–

116,8±8,0

87,3±5,5*

Free testosterone, pmol/L

226±43

248±37

–

–

Dihydrotestosterone, nmol/L

1,7±0,1

1,6±0,2

–

–

Estradiol, pmol/L

296±55

309±49

–

–

Progesterone, nmol/L

0,48±0,23

0,30±0,09

–

–