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Features of the kinetic curves of caffeine in urine that are dose-dependent in induced fatty liver disease
Table 1 - Urinary caffeine levels after exogenous caffeine administration
Administered dosage of the medicine (calculated as pure caffeine) | 50 mg/kg | 100 mg/kg | 150 mg/kg | |||
T after injection / sex of animals | ♂ | ♀ | ♂ | ♀ | ♂ | ♀ |
1 hour | 1,047±0,21 | 1,099±0,16 | 3,600±0,812 | 3,525±0,417 | 6,590± 0,920 | 6,110±0,943 |
4 hours | 1,207±0,78 | 1,238±0,39 | 5,281±0,504 | 5,098±0,542 | 7,494±0,673 | 7,056±0, 788 |
8 hours | 1,921±0,24 | 1,949±0,82 | 5,457±0,906 | 5,729±0,893 | 8,468±1,023 | 8,650±1,047 |