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ANALYSIS OF SDHx EXPRESSION IN VAGAL PARAGANGLIOMAS
Table 1 - Relative SDHx expression levels in VPGs and correlations with mutations
Gene | Decrease, % | Increase, % | Max increase, times | Max decrease, times | Average change, time | Spearman correlation coefficient | P value (Spearman test) |
SDHA* | 54.5 | 15 | 4 | 6 | 1.6 | - | - |
SDHB | 61 | 12 | 4.5 | 6 | 1.4 | -0.21 | 0.20 |
SDHC* | 23 | 60 | 31.8 | 171 | 3.7 | - | - |
SDHD | 20 | 48 | 26.5 | 34 | 0.7 | -0.10 | 0.64 |
* - due to the lack or low number of mutations in SDHA, correlation was not assessed