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MEDICINE

ISSN 2227-6017 (ONLINE), ISSN 2303-9868 (PRINT), DOI: 10.18454/IRJ.2227-6017
ПИ № ФС 77 - 51217, 16+

TEMPERATURE OF ACTIVE AREAS OF SKIN AT DIFFERENT HUMAN’S FUNKCIONAL STATES

Posted in 2014, Issue February 2014, MEDICINE | 0 comments

In the article present of features temperature changes in the active and contiguous areas of skin at the psychophysiological loadings which influence on the human functional states. These changes can be used for a correction, normalization and optimization of the functional states.

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DESCRIPTION CASE OF MISTAKEN DIAGNOSIS OF ACUTE MYOCARDIAL INFARCTION IN PATIENTS WITH HYPERTROPHIC CARDIOMYOPATHY

Posted in 2014, Issue February 2014, MEDICINE | 0 comments

Relevance. Diagnosis of hypertrophic cardiomyopathy causes considerable difficulties. This status has been little studied . Purpose . Identify the relationship of clinical, ECG and echocardiography manifestations and differentiate this pathology myocardial infarction . Method . Description of the case. Result. Diagnosis postinfarction Cardiosclerosis was made on the basis of teeth in QS levogrudnyh leads (V5-V6), and angina based on microcirculatory anginal pain character. Conclusion . ECG changes in hypertrophic cardiomyopathy are found in 90% of patients : changes in segment ST, the presence of pathological Q waves and QS. To perform coronary angiography revealed no pathological changes that allowed us to exclude myocardial infarction . Thus, the diagnosis of hypertrophic cardiomyopathy was made sick by exclusion of CHD , angina and postinfarction Cardiosclerosis .

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POTENTIAL ROLE OF A PROINFLMMATORY CYTOKINES IN POSTOPERATIVE SEVERE SYSTEMIC INFLAMMATORY RESPONSE SYNDROME UNDERGOING HEART VALVE REPLACEMENT SURGERY

Posted in 2014, Issue February 2014, MEDICINE | 0 comments

The article presents the results, obtained in the study aimed at the determination of the significance of key markers of acute-phase inflammatory response in the early postoperative period in cardiac patients.

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OSTEOPOROSIS AND SEVERE PAIN PATIENTS WITH BREAST CANCER OF REPRODUCTIVE AGE

Posted in 2014, Issue February 2014, MEDICINE | 0 comments

In article – revealing the incidence of osteoporosis in breast cancer patients of childbearing age, the relationship with the severity of pain in osteoporosis need for timely administration of drugs that prevent the development of osteoporosis and as a consequence, lead to a decrease in pain and improved quality of life for women.

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THE ROLE OF CELL INTERACTIONS IN REGENERATION PROCESS OF THE THYROID GLAND IN CHRONIC ENDOGENOUS INTOXICATION

Posted in 2014, Issue February 2014, MEDICINE | 0 comments

The study aims to explore the thyroid cell regeneration in chronic endogenous intoxication associated with various somatic pathologies. Remodeling of thyroid parenchyma due to prolonged exposure to endogenous toxic substances results in the isolation of follicles which may underlie the formation of neoplastic thyroid nodules as well hormonal imbalance.

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NEW APPROACHES TO CANCER PATIENTS TO SUPERVISION IV CLINICAL GROUP

Posted in 2014, Issue February 2014, MEDICINE | 0 comments

Based on the analysis of the structure of oncological patients IV clinical group and time frames for their survival, the results of surveys of patients, their relatives, family therapist expedience specialized palliative care, standards of tactics to supervision by doctors, therapists, generalized cancer patients.

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MEDICAL AWARENESS AS A KEY COMPETENCE IN THE FORMATION OF THE HEALTHY WAY OF LIFE OF THE URBAN POPULATION

Posted in 2014, Issue February 2014, MEDICINE | 0 comments

With the help of a specially designed program of medical and sociological studies the influence of medico-social aspects of medical awareness on the formation of attitudes for healthy way of life was studied. The peculiarities of the main types of the functioning in the structure of the quality of life of the population were revealed. A justification of measures of increasing of the prophylactic activity and complex improvement of the health of the urban population was held.

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ASSESSMENT OF MORBIDITY AND REHABILITATION ACTIVITIES OF PATIENTS WITH ICP: ANALYSIS OF EFFICIENCY (BASED ON SURVEY OF PARENTS OF PATIENTS IN CHILDREN REGIONAL CLINICAL HOSPITAL No. 1)

Posted in 2019, Issue № 5(83) May 2019, MEDICINE | 0 comments

The article presents the results of a small statistical study conducted in the neurological department of the children regional clinical hospital No. 1 in Saransk. The incidence of children of different ages was studied; parents of children diagnosed with cerebral paralysis were interviewed about the effectiveness and success of the rehabilitation activities carried out at the medical institution, about the dynamics of the subsequent state of the child. Based on the analyzed data, a subsequent assessment of the importance and usefulness of this treatment course for sick children and their parents is given.

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EPIDEMIOLOGICAL ASPECTS OF POST-CARDIOSURGICAL SEPTIC-PURULENT INFECTIONS BASED ON BASIC DIAGNOSIS

Posted in 2019, Issue № 5(83) May 2019, MEDICINE | 0 comments

Over the last decade, healthcare associated infections (HAI) have been increasingly alarming as a public health problem even in developed and industrialized countries. These infections have a specific epidemiological aspect in hospitals with different medical profiles. This study demonstrates the acquisition of septic-purulent nosocomial infections in the hospital with cardiosurgical profile depending on the basic diagnosis. It has been shown that the incidence of post-cardiosurgical septic-purulent infections is higher in emergency patients, most post-cardiosurgical septic-purulent infections are recorded in patients undergoing bypass, bypass plus one prosthesis plus one plasty, bypass plus one prosthesis plus two plasties, bypass plus one plasty, bypass plus two prostheses plus one plasty, having the diagnosis of cardiopathy, dissecting aneurism (Marfan syndrome), defect of aortic / mitral/ tricuspid valve, endocarditis, cardiopathy.

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DETERMINATION OF BIOLOGICAL AGE IN PENSIONERS

Posted in 2019, Issue № 5(83) May 2019, MEDICINE | 0 comments

Objective: to study the biological age of retirees.

Goal:

To study the literature on the topic of biological age;
Conduct test and physical studies of biological age;
Determine the health status of the subjects;
Determine the dependence of biological age indicators on the type of activity;
Analyze the results.
Object: Groups of elderly and middle-aged people.

We have examined 27 people aged from 41 to 84 years. (among them: 16 still work, and 11 are pensioners.) The study of biological age was carried out according to V. P. Voitenko’s method.

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DISTRIBUTED COMPUTING SYSTEMS FOR MODELING PROTEIN STRUCTURES IN PHARMACY AND MEDICINE

Posted in 2019, Issue № 5(83) May 2019, MEDICINE | 0 comments

This article discusses modern advances in computer modeling of various biological systems at the level of protein structures with the use of distributed computing systems (for example, supercomputers and grid computing systems). At each example or a group of similar examples at the end of the narrative, possible directions for their application in the field of medicine and pharmacy are attached. Thus, a reader forms a holistic view of the given simulated biosystems from the initial stage of the study to the further found or even predicted practical application of the results obtained in practice.

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CHARACTERISTIC OF THE CONDITIONS OF EDUCATION AND TRAINING PUPILS OF 12-14 YEARS IN THE FAMILY

Posted in 2014, Issue January 2014, MEDICINE, Выпуск Январь 2014 | 0 comments

In article the analysis of the factors defining health of pupils of middle classes is presented. In researches questioning for the purpose of studying of the reasons of formation of deviations in health and diseases at children was applied. It is revealed that lifestyle has the main impact on health of the person.

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ESTIMATION OF FACTORS OF THE HEALTH OF SCHOOLCHILDREN

Posted in 2014, Issue January 2014, MEDICINE | 0 comments

In article the analysis of the factors defining health of pupils of middle classes is presented. In researches questioning for the purpose of studying of the reasons of formation of deviations in health and diseases at children was applied. It is revealed that lifestyle has the main impact on health of the person.

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DIAGNOSIS AND TREATMENT OF MYOGENIC FACIAL PAIN

Posted in 2014, Issue January 2014, MEDICINE, Выпуск Январь 2014 | 0 comments

It is shown that myogenic painful phenomenon of the face violates the act of chewing of food and may be caused by the gipertonus of muscles that accompanies bruxism and the focal dystonia facial muscles. Found that surface electromyography allows to determine an increased electrophysiological activity, and infrared thermography facial skin allows to detect the increased temperature of the skin in the area of projection of muscles, having gipertonus. Found that injection of hard temporal or chewing muscle of botulinum toxin A in a dose of 15 – 20 or 30 – 50 Units Steps (respectively) effectively reduces facial myogenic pain, gipertonus and increased electrophysiological activity of these muscles, local hyperthermia skin in the field of its projection, bruxism, the focal dystonia muscles and normalizes the act of chewing of food.

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SEARCH FOR NEW SOURCES OF VITAMINS AND ANTIOXIDANTS SOUTH URAL

Posted in 2014, Issue January 2014, MEDICINE, Выпуск Январь 2014 | 0 comments

Given the important role of carotenoids in the normal metabolism of cells, an urgent task of modern medical and biological science is the search for natural resources and the assessment of its quality. Wild plants are a promising source of carotenoids for health care. The article presents data on the content of carotenoids in plants sage steppe and nettle, used by the population of the Southern Urals and adjacent regions as medicinal plants, as well as a source of vitamins in the spring and summer. The authors identified the level of flavonoids in raw said plants collected in conditions of technogenic pollution and ecologically clean area.

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THE ROLE OF PROPROTEIN CONVERTASE SUBTILISIN/KEXIN OF TYPE 9 (PCSK-9) IN CHOLESTEROL METABOLISM AND NEW OPPORTUNITIES OF LIPID CORRECTIVE THERAPY

Posted in 2019, Issue №4(82) April 2019, MEDICINE | 0 comments

Proprotein-convertase subtilisin/kexin of type 9 (PCSK-9) is an essential enzyme that regulates the circulating levels of low-density lipoprotein (LDL), due to its central role in the destruction of low-density lipoprotein receptors (RLPN) located on the surface of hepatocytes. The literature review examines the key studies that allowed us to establish the mechanism of action of PCSK-9, which has led to the development of a new class of lipid-lowering drugs – PCSK-9 inhibitors.

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TRASTUZUMAB-INDUCED CARDIOTOXICITY – INTERDISCIPLINARY PROBLEM OF MODERN MEDICINE

Posted in 2019, Issue №4(82) April 2019, MEDICINE | 0 comments

Trastuzumab is the basis of adjuvant therapy for HER2 positive breast cancer. This fact is confirmed by currently received remote (more than five years) results of clinical studies. Although trastuzumab is devoid of classical toxicity in the treatment of cancer, its symptomatic and asymptomatic effects on heart function are of great concern. This drug is characterized by the second type of cardiotoxicity (reversible cardiotoxicity). The meta-analysis devoted to the development of cardiotoxicity in patients with breast cancer, taking trastuzumab, showed that 3% of all patients experienced severe cardiotoxicity. In modern clinical practice, patients often have cardiovascular diseases, so it is impossible to go without a proper assessment of the risks of the upcoming treatment. According to the author’s opinion, the best solution to this problem is interdisciplinary interaction between cardiologists and oncologists.

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ULTRAMICROSCOPIC ANALYSIS OF THE STATE OF NUCLEAR STRUCTURES OF NEUROBLASTS AND GLIOBLASTS OF THE HUMAN BRAIN CORTEX IN NORMAL CONDITIONS AND IN THE CONDITIONS OF THE MOTHER’S PRENATAL ALCOHOLIZATION

Posted in 2019, Issue №4(82) April 2019, MEDICINE | 0 comments

A complex of morphological changes in the structure of the nucleus of neuroblasts and glioblasts in the conditions of prenatal alcoholization was established during the ultrastructural analysis of 53 brain samples of embryos and human fetuses of 7-12 weeks of development. Vacuolization of the perinuclear space, rearrangement of the inner and outer membranes of the nucleus, and the formation of 3 types of specific spheroid structures near the outer nuclear membrane were revealed. These ultrastructural manifestations of nuclear reaction indicate one of the points of application of the alcoholic effects of the developing brain cells.

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IMPROVING APPROACHES IN CARRYING OUT ASSISTED VENTILATION IN PATIENTS WITH HEAVY PNEUMONIA

Posted in 2019, Issue №4(82) April 2019, MEDICINE | 0 comments

The article presents an analysis of the dynamics of respiratory pattern sizes in patients with severe pneumonia. The combination of respiratory parameters in this group of patients has been determined, contributing to the ensuring comfortable conditions and the maintenance of blood gas composition during the period of respiratory support. The dynamics of blood gas composition was analyzed during the phased transfer of patients of this profile to independent breathing. The work focuses on the gradual decrease in FiO2 (fractional concentration in the inhaled mixture) to prevent the development of hypoxemia and prevent exhaustion of the respiratory muscles throughout the duration of assisted ventilation.

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ANALYSIS OF RESULTS OF SEVERE CONCOMITANT INJURIES TREATMENT

Posted in 2019, Issue №4(82) April 2019, MEDICINE | 0 comments

The results of treatment of victims with severe concomitant injuries in risk situations, the extreme necessity and experiment are stated. Based on the analysis of the treatment results, it was revealed that the quality level of the solutions in the indicated situations was as follows: diagnostics – 0.76; tactics – 0.67; equipment – 0,69. Whereas, the level of the quality of medical and surgical care should comprise 2.0-3.3 in general. This situation is information for consideration for health care managers and all surgical specialists who are faced with the problem of providing medical and surgical care for severe concomitant injuries.

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