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MEDICINE

ISSN 2227-6017 (ONLINE), ISSN 2303-9868 (PRINT), DOI: 10.18454/IRJ.2227-6017
ПИ № ФС 77 - 51217, 16+

STATE OF PRO-AND ANTICOAGULATION SYSTEMS OF PREGNANT WOMEN WITH GESTATIONAL DIABETES MELLITUS

Posted in 2014, Issue May 2014, MEDICINE | 0 comments

The aim of this work was to study the state of the pro-and anticoagulant systems in pregnant women with gestational diabetes mellitus structure and methods of delivery complications in this group of pregnant women.

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THE EVALUATION TOOLS OF THE CNS IN CARDIAC SURGICAL PATIENTS

Posted in 2014, Issue May 2014, MEDICINE | 0 comments

The article discusses the possibility of thermal telemetry studies of cerebral vessel . Found significant correlations between brain activity and thermal picture of the corresponding projections of cerebral vessels in cardiac patients, which allows the use of thermography as a method of informative method for timely diagnosis predictors of critical states.

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CEREBRAL PALSY: NEW IN REHABILITATION QUESTIONS

Posted in 2014, Issue May 2014, MEDICINE | 0 comments

Cerebral palsy belongs to group of permanent disturbances of development of movements and position of the body, generating restriction of activity and caused by an improgressive lesion of a developing brain of a fetus or the child. At cerebral palsy there is no universal method of rehabilitation, thus it is necessary to unite to different forms and treatment methods in a complex to correctional psychological and pedagogical work. Such methods, as use of system of intensive neurophysiological rehabilitation, a reflexotherapy combination with cortexin and neuroprotective treatment about which speech in this article will go became most widespread.

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PLACENTAL MALFUNCTIONS DURING PREGNANCY AFTER RECONSTRUCTIVE OPERATIONS ON UTERUS

Posted in 2019, Issue № 12(90) December 2019, MEDICINE | 0 comments

The problem of the development of placental insufficiency during pregnancy takes a special place in obstetric practice. The goal of this work is to study the features of the development of the placental disorder during pregnancy that occurred after the surgical correction of uterine malformations.

The authors conducted a survey of 30 patients who became pregnant in a natural way after corrective operations on the uterus. The control group consisted of 40 pregnant women with an uncomplicated course and normal uterine anatomical structure. The leading complications of pregnancy after undergoing operations on the uterus are as follows: a compensated form of placental insufficiency and the threat of miscarriage.

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DRUG EFFECT ON LABORATORY TEST RESULT ON NARCOTIC AND PSYCHOTROPIC SUBSTANCES

Posted in 2019, Issue № 12(90) December 2019, MEDICINE | 0 comments

A wide range of specialties is subjected to laboratory testing for the presence of narcotics and psychotropic substances in biological fluids according to the laws of the Russian Federation. In most cases, an immunochromatographic analysis is used for that, but a significant drawback of this method is the possibility of a false-positive test result. The reason for this may be in cross-reactions occurring in a body due to the use of drugs that are not related to the groups of narcotics and psychotropics. Studies show that false positives for amphetamines are most common. So, the goal of this study is a detailed consideration of this phenomenon, as well as a review of drugs that can imitate the appearance of a metabolite of a psychotropic substance in a human body. The data obtained can be used both in research and in practical activities of biologists, pharmacists, pharmacologists and clinicians of various specialties.

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COMPLEX DIAGNOSTICS OF REPEATED VOMITING

Posted in 2019, Issue № 12(90) December 2019, MEDICINE | 0 comments

Cyclic vomiting syndrome is a pathological state in which a patient experiences at least three separate attacks of vomiting, each of which is accompanied by more than four vomiting episodes at the height of the disease. In typical cases, no more than two episodes per week are observed. The average duration of an attack is 24-48 hours (minimally 2 hours), but it can last for 10 days or more. The duration of the intervals when a patient is free from vomiting and is practically healthy is different. Isovaleric acidemia has similar symptoms.

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TEAM EFFECTIVENESS PROGRAMS FOR MEDICAL PERSONNEL OF NON-EMERGENCY ASSISTANCE

Posted in 2019, Issue № 12(90) December 2019, MEDICINE | 0 comments

The paper presents the overview of foreign programs intended to improve the quality of teamwork of medical personnel on an outpatient basis, in long-stay patients and primary health care departments, as well as rehabilitation clinics. It is shown that the basis of most programs are theoretical and practical seminars, during which great attention is paid to the development of “non-technical” skills of staff: setting common goals for the team, effective communication, mutual assistance in decision making, leadership, situational awareness, and self-confidence. The high efficiency of the practical use of methodological developments and interactive courses in various countries and areas of medical care is shown in this work. At the same time, many courses are adapted for just a strictly defined medical field, while there are still very few programs tested in the clinical setting and suitable for workers in different medical fields. In this regard, it is relevant to expand the profile of programs to improve the quality of teamwork of medical personnel and apply the already gained experience with the adaptation of the programs considered in work for Russian healthcare.

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TREATMENT OPTIONS FOR ASEPTIC NECROSIS OF FEMORAL HEAD

Posted in 2019, Issue № 12(90) December 2019, MEDICINE | 0 comments

Aseptic necrosis of the femoral head is one of the most important problems in traumatology; it causes a gradual deformation of the femoral head at the places where the greatest load is applied to it. The disease is the cause of disability in 7% of the total number of orthopedic patients with dysfunction of the lower extremities. There are various surgical and conservative approaches to the treatment of this pathology. This article presents an overview of the available data on the use of these methods for the correction of osteonecrosis of a hip joint.

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THE ACTIVITY OF METABOLIC PROCESSES IN THE MANDIBULAR BONE TISSUE OF WHITE RATS USING COORDINATION COMPOUNDS OF ZINC (EXPERIMENTAL STUDY, STAGE 1)

Posted in 2019, Issue № 12(90) December 2019, MEDICINE | 0 comments

To determine the functional state of mineralized tissues in the simulation of experimental periodontitis, markers of formation and resorption were studied, lysozyme activity of enzymes, indicators of adenylic nucleotide metabolicity, glucose and dehydrogenase activity of the Krebs cycle, as well as the content of deoxyribonuleric acid, calcium and phosphorus. The study of the effect of 11 coordination compounds of zinc on osteoregenerative processes under normal physiological conditions was conducted on 96 rats weighing 180–220 g. The most biologically active was the coordination compound of zinc — an adduct of zinc trifluoroacetate with y-picoline with the general formula Zn(CF₃CO₂)₂(γPic)₂. The optimal dose for administering Zn trifluoroacetate Adduct with γ-picoline was analyzed on 36 rats, divided into 5 groups, and control (0.25 mg; 0.5 mg; 0.75 mg; 1 mg; 1.25 mg Zinc in weight 100 g) Biochemical results showed that the most optimal was 1.0 mg Zn / 100 g corp. weight). The use of zinc trifluoroacetate adduct with y-picoline in animals that were used to simulate experimental periodontitis has a positive effect on the intensity of the formation and resorption of bone tissue of alveolar apophysis, which is manifested in a decrease in the number of sectors of alveolar apophysis of the lower jaw with resorption relative to the control group for radiovisiographic of the lower jaw of the animals included in the study. In experimental periodontitis, there are significant changes in the lipid peroxidation system – antioxidant protection, which is characterized by an increase in the level of lipid hydroperoxidants and malonic dialdehyde, a decrease in the overall antioxidant activity and ca-talase. Excessive development of reactive oxygen species and the apparent lack of anti-acidic factors is a solid support for the suggestion that oxidative stress plays an important role in the pathogenesis of experimental periodontitis.

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STUDY OF ADSORPTION OF PURE AND MODIFIED SUPERCRITICAL CARBON DIOXIDE BY POLYETHYLENE OF MEDICAL PURPOSE

Posted in 2019, Issue № 12(90) December 2019, MEDICINE | 0 comments

This paper considers the effect of pure and modified supercritical carbon dioxide on 5118 polyethylene in order to determine the possibility of using supercritical fluids as a sterilizing agent for medical devices made of polymer materials. The authors also describe the instrumentation and the technique of an experiment to study the adsorption of supercritical CO2 by polyethylene. They revealed the lack of solubility of the test polymer material in the sterilant.

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ENDOVASCULAR TREATMENT OF PATIENTS WITH DISTAL FORM OF ARTERIAL INVOLVEMENT IN LOWER LIMBS UNDER DIABETIC MACROANGIOPATHY

Posted in 2019, Issue № 12(90) December 2019, MEDICINE | 0 comments

The paper presents the data of scientific and clinical work on the distal blood flow restoration in 58 patients (66 endovascular procedures) based on the results of endovascular correction of critical lower limb ischemia in patients with diabetic macroangiopathy. 46 patients (79.3%) passed interventions in the popliteal and tibial arteries. Balloon angioplasty of the superficial femoral artery was carried out in 9 cases (15.5%), popliteal – in 12 patients (20.7%), tibial arteries – in 21 cases (36.2%). Stenting of the superficial femoral artery was performed in 11 patients (19%), the popliteal artery – in 5 (8.6%), and tibial arteries – in 8 patients (13.8%). The results were analyzed in the hospital, close and distant (6 and 12 months) periods. Immediate angiographic success was recorded in all patients. Cumulative patency of the operated arteries by the end of 1 month after surgery was noted in 93.1% of cases. After six months, blood flow was preserved in 84.5%, and after a year in 77.5% of patients. Mortality directly related to the disease in question is not noted.

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COMPARATIVE ANALYSIS OF INFLUENCE OF PARENTERAL NUTRITION METHOD ON METABOLISM OF PATIENTS WITH ACUTE SEVERE PANCREATITIS

Posted in 2019, Issue № 11(89) November 2019, MEDICINE | 0 comments

The authors analyzed the data on patients with severe acute pancreatitis (AP) who were treated during the period from 2014 to 2018. Nutritional support was started with full parenteral nutrition (FPN) for patients who showed symptoms of intestinal insufficiency on the second day of intensive care, which made it impossible to conduct early enteral nutrition. Depending on the type of mixture that was used as nutritional support, patients were divided into subgroups: subgroup No.1 (n = 22) included patients who received three-component mixtures in special bags for FPN. Subgroup No.2 (n = 20) included patients who received triple-component mixtures with increased content of ѡ-3 fatty acids for FPN. Subgroup No.3 (control) included patients (n = 25) who got FPN with separate modules of carbohydrates, amino acids, and lipids.

Conducting modular PN did not provide a protein-saving effect against the background of hypercatabolism caused by severe AP, was accompanied by an increase in the number of complications during the early phase of the disease (R = 0.797, p = 0.005) and an increase in the length of hospitalization (R = 0.643, p = 0.051).

The addition of ԝ-3 FA to the composition of mixtures in three-chamber bags for parenteral nutrition contributed to a more rapid restoration of the level of total protein, albumin, and blood glucose in the presence of severe AP (R = 0.783, p = 0.037).

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INFLUENCE OF PRODUCTION FACTORS ON THE STATE OF A MEDICAL SPECIALIST’S ORGANISM

Posted in 2019, Issue № 11(89) November 2019, MEDICINE | 0 comments

Организм медицинского работника находится в окружении неблагоприятных факторов производственной среды, под влиянием которых возможно развитие различных психофизиологических дисфункций. В данной статье был проведен анализ напряженности труда медицинских работников нескольких больниц г. Санкт-Петербурга с выявлением у них психосоматических патологий. На основании полученных результатов было сделан вывод о том, что сотрудники обследованных больниц в средней степени адаптированы к стрессовым воздействиям на свой организм.

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PREVALENCE OF IODINE DEFICIENCY STATES IN SCHOOL CHILDREN

Posted in 2019, Issue № 11(89) November 2019, MEDICINE | 0 comments

Currently, the problem of iodine deficiency remains very significant, which is associated with a high degree of its prevalence, a wide range of manifestations and consequences, especially among children who are most vulnerable. This article presents key questions on the role of iodine and thyroid hormones in the functioning of the body and the consequences of iodine deficiency. The spectrum of iodine deficiency pathology is presented, data on the prevalence of iodine deficiency states of children and adolescents and the methods used in the course of work are highlighted. The study was conducted among school-aged children (from 7 to 12 years old) who underwent treatment at the Lastochka Sanatorium in Izhevsk. We used the technique developed by Khlebnikova L.N. – a table with indicators and a diagnostic coefficient (DC) – to identify the risk group.

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INKRETINOMIMETIKS: LOOK AT THE EFFICACY AND SAFETY

Posted in 2014, Issue April 2014, MEDICINE | 0 comments

The article examined and compared the performance of two groups of hypoglycemic drugs and inkretinomimetikov biguanide, as well as their impact on the body mass index (BMI), to evaluate the likelihood of one of the possible side effects – acute pancreatitis. When credible evidence of efficacy inkretinomimetikov particularly exenatide, its positive impact on the reduction of BMI and the lowest probability of acute pancreatitis, will allow the most widely used in the preparation of this group for the purpose of effective and safe control of type 2 diabetes by obesity.

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INTENSITY THE EXPRESSION MARKERS OF ACTIVATION LEUKOCYTES AT INTRODUCTION B. ABORTUS 19 BA

Posted in 2014, Issue April 2014, MEDICINE | 0 comments

The assessment of intensity an expression markers activation of leukocytes of experimental biomodels is carried out, at immunization B. abortus 19 BA. The increase in intensity an expression of receptors IL – 2 and IL – 4 on population monocytes and neutrophils during the period from 5 to 14 days after vaccination against a brucellosis is established. Considering the leading role an anti-gene – presenting cages in an initial stage of immunogenesis, detection of intensity of an expression of receptors to IL 2 and 4 allows to define a functional condition of phagocytes in response to immunization, and respectively can act as a marker at an assessment of efficiency actions for specific prevention a brucellosis.

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METHODICAL PROBLEMS OF CHEMICAL AND ANALYTICAL SAFETY OF PRODUCTS GROWN WITH APPLICATION OF DITHIOCARBAMATES

Posted in 2014, Issue April 2014, MEDICINE | 0 comments

The article presents the results of the research of the significance of biodegradation ethylene-bis-dithiocarbamate formulations with the formation of ethylenethiourea in agricultural products (grapes, cucumbers, onions, potatoes, tomatoes) and some processed products.

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SOCIAL ORPHANHOOD – THE REALITIES OF MODERN LIFE

Posted in 2014, Issue April 2014, MEDICINE | 0 comments

The article is devoted to the problem of social orphanhood in modern society. Based on the data of statistics revealed the main reasons and factors contributing to the fact that children with living parents live in orphanages and other specialized institutions. Analyzed further destiny and features individual development of these unhappy children. Some positive dynamics in solving the problem is showed. In considering the situation in the Volga Federal district. Effectiveness of active social orphanhood prevention, its main areas and the need for further improvement.

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METHOD NONSPECIFIC ANTICYTOKINE THERAPY OF GENERALIZED FORMS OF SURGICAL INFECTIONS

Posted in 2014, Issue April 2014, MEDICINE | 0 comments

The results of the clinical use of pentoxifylline as a nonspecific anti-cytokine therapy of generalized surgical soft tissue infections. In a comparative analysis, proved to be efficient for Pentoxifylline suppression of the synthesis and the reduction of TNF levels, which option enabled affect the course of infection and shorten cupping systemic inflammatory response.

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IMAGING OF THE TEMPORAL BONE: LITERATURE REVIEW

Posted in 2014, Issue April 2014, MEDICINE | 0 comments

The question of choosing the optimal method and visualization techniques of temporal bone is relevant because resulting from the survey information allows to decide on further conservative or operative treatment strategies and their content. The paper is made of the history of the temporal bone imaging, defined modern realities, outlined the prospects; formulate conclusions regarding the choice of methods and means of temporal bone imaging in various pathological conditions.

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