Pages Navigation Menu
Submit scientific paper, scientific publications, International Research Journal | Meždunarodnyj naučno-issledovatel’skij žurnal

MEDICINE

ISSN 2227-6017 (ONLINE), ISSN 2303-9868 (PRINT), DOI: 10.18454/IRJ.2227-6017
ПИ № ФС 77 - 51217, 16+

ADIPOKINES IN RHEUMATOID ARTHRITIS

Posted in 2014, Issue November 2014, MEDICINE | 0 comments

We studied adiponectin and visfatin levels in blood of 55 rheumatoid arthritis patients. We found a relationship between the concentration of adiponectin, visfatin and severity of rheumatoid arthritis.

Read More

DIAGNOSIS AND TREATMENT OF FLOATING PHLEBOTHROMBOSIS OF THE LOWER EXTREMITIES

Posted in 2014, Issue November 2014, MEDICINE | 0 comments

The article is devoted to the diagnosis and surgical prevention of pulmonary embolism in the phlebothrombosis of the lower extremities. It is established that the CBC is an informative method of diagnostics of floating blood clots. Urgent implantation of cava filter, cava or veinplication, crossectomy are effective ways of prevention of pulmonary embolism. After surgery, it is advisable to carry out adequate thrombolytic and antiplatelet therapy for the correction of coagulation disorders, treatment and prevention of progressive phlebothrombosis.

Read More

MORPHOLOGICAL PARAMETERS OF PANCREAS IN DEPENDENCE OF SOMATOTYPE, GENDER AND AGE BELONGING OF A HUMAN

Posted in 2014, Issue November 2014, MEDICINE | 0 comments

The objective of work is to establish gender and typical differences in biometrical parameters ultrasonic anatomy of pancreas in elderly people.

Task of the work:

– to establish gender and typical differences of anatomic structure of pancreas;

– to determine gender, somatometric and somatypical conditionality in biometrical parameters of pancreas.

Practical significance: the field of gastroenterological researches.

Read More

PHYSICAL DEVELOPMENT OF SCHOOLCHILDREN FIFTH CLASS

Posted in 2014, Issue November 2014, MEDICINE | 0 comments

In the article some anthropometric indicators and conducted a comprehensive assessment of physical development method sigmaline deviations of the students of 5th class.

Read More

THE DIFFICULTIES OF FORMING RISK GROUPS FOR DEVELOPING PULMONARY HYPERTENTION IN YOUNG AND MIDDLE-AGED MEN WITH MYOCARDIAL INFARCTION

Posted in 2020, Issue № 08(98) August 2020, MEDICINE | 0 comments

The topicality of the research topic. Pulmonary hypertension (PH) significantly worsens the prognosis of myocardial infarction (MI) and the quality of life of the patients.

The goal of the research. To develop a model for estimating the risk of developing PH in the subacute period of MI to predict and prevent this illness in a prompt manner.

Materials and methods of the research. 666 men aged 32-60 with MI participated in the research. Patients underwent a standard diagnostic algorithm, including complex echocardiography which was made in the first 48 hours and at the end of the third week of the disease period. The study group consisted of 100 patients with PH, which appeared at the end of the third week of the disease (MI). Initially mean pulmonary arterial pressure (mPAP) was at a normal level. The control group included 566 patients with normal mPAP levels during the both phases of the study or those with the normalization of this indicator at the end of the subacute period of the disease. Using multivariate analysis of variance (ANOVA), indicators that have a significant impact on the risk of PH at the end of the subacute MI period were selected from the analytical database. They were used to build a predicative model of the possible risk of this event using classification trees method.

The results of the research. A prognostic algorithm has been developed. It includes three risk classes (from 10.1 to 37.5%) based on the assessment of the blood plasma sodium level and the index of the final systolic volume of the left ventricle in the first hours of MI. It has certain characteristics that allow the authors of the research to recommend its use during regular clinical practice as an addition to the existing standards for assessing the risk of PH in the subacute period of MI.

The conclusions. The use of this algorithm for prognostic modeling in the initial periods of MI in order to identify a risk group for developing PH in its subacute period will help improve the results of treatment of this pathological condition. However, some characteristics of the algorithm indicate the need for further improvement.

Read More

SURGICAL TREATMENT OF THE PATIENTS WITH PRIMARY ALDOSTERONISM

Posted in 2020, Issue № 08(98) August 2020, MEDICINE | 0 comments

In this article, the author analyzes the results of surgical treatment of 568 patients with primary aldosteronism (PA). Patients were divided into 2 groups depending on the level of surgical intervention: the first (control) group consisted of the patients who underwent adrenalectomy – 301 (53%) people; the second (main group) – consisted of the patients with adrenal resection – 267 (47%) people. The indications for adrenal resections were: a verified diagnosis of PA; adenoma size from 0.5 to 3.0 cm; bilateral lesion. In the immediate postoperative period, blood pressure (BP) decreased in 89.5% (239 people) of patients in the first group and in 93% (280 people) of patients in the second group. Thus, adrenal resections are an adequate surgical procedure that in most cases allows to achieve the necessary clinical effect.

Read More

FORENSIC ANALYSIS OF THE DAMAGE MADE BY IMPROVISED WEAPONS AS THE CAUSE OF DEATH (OBSERVATION FROM PRACTICE)

Posted in 2020, Issue № 08(98) August 2020, MEDICINE | 0 comments

The forensic medical examination of a firearm injury is one of the most complex types of examinations in the practical work of forensic medical experts. One of the important stages of the medical forensic examination of firearms injuries refers to the primary investigative action, examination of the corpse at the place of discovery of crime. According to Criminal Rule 178 of the Russian Federation Code of Criminal Procedure, the investigator examines the corpse with the participation of a forensic expert, and if there’s no such expert – a doctor can be enlisted to help. In this article, the authors describe the case of death of an oncological patient as a result of a shot from an improvised weapon. Standard research methods used in forensic medicine and criminology were used during the research process.

Read More

PSORIASIS AND COMORBID CONDITIONS: NEW APPROACHES TO THERAPY

Posted in 2020, Issue № 08(98) August 2020, MEDICINE | 0 comments

Two groups of patients with widespread psoriasis vulgaris with cardiological and neurological pathology were examined, in order to study the effect of complex therapy (group I patients (n=35)) and therapy with coenzyme Q10 (Kudesan) (group II patients (n=35)) on the dynamics of the clinical picture and the indicators of endogenous intoxication and antioxidant protection. In the course the study, the presence of endogenous intoxication syndrome was revealed (high values of MDA and Fe-MDA of blood plasma and red blood cells, DKe and DKo). At the same time there was antioxidant system depression (low values of red blood cell catalase, SOD and RLPO of blood plasma) with further reliable correction of indicators under the influence of therapy with included Kudesan.

Read More

NEW ASPECTS OF ASSESSMENT OF ADAPTATION TO PHYSICAL EXERTION: ATHLETE’S HEART AND TRANSMITRAL BLOOD FLOW IN THE CONDITIONS OF AEROBIC-ANAEROBIC METABOLISM OF MUSCLE ACTIVITY

Posted in 2020, Issue № 08(98) August 2020, MEDICINE | 0 comments

In this article, the authors describe the indicators of transmitral blood flow that reflect the state of aerobic and anaerobic glycolytic mechanisms of energy supply of muscle activity, that influences the areas of high, submaximal and maximum power. These indicators also allow to estimate the training level of of qualified athletes.

Read More

MEDICAL SERVICES EXPORT IN ROSTOV REGION: PROBLEMS AND DEVELOPMENT PROSPECTS

Posted in 2020, Issue № 07(97) July 2020, MEDICINE | 0 comments

The paper considers the main social and economic indicators of the medical service export. SWOT analysis of factors affecting the development of medical services exports was carried out as part of the study. The authors note that the lack of legal regulation, the reputational costs of Russian health care, and administrative barriers are the determining threats to improving medical tourism as a key form of medical services export. The problems of accounting volume of such medical services provided at the regional level are identified by analyzing reporting forms of statistical observation. The results show that it is necessary to develop regional medical clusters that allow for both interdepartmental interactions of state and municipal authorities, and the active involvement of business structures in order to develop inbound medical tourism further.

Read More

PROLAPSE OF PELVIC ORGANS IN WOMEN OF REPRODUCTIVE AGE

Posted in 2020, Issue № 07(97) July 2020, MEDICINE | 0 comments

Prolapse of pelvic organs (PPO) in women can appear not only during the perimenopausal period but also in patients of reproductive age. The authors analyzed 16 cases of PPO in women under the age of 40 years; their average age is 33.1 ± 0.9 years. The most frequent complaints of women in this study are as follows: discomfort in the perineum – 73.3%, urinary incontinence when coughing and sneezing (28.6%), in 15.8% of cases, patients noted periodic astrictions and in 5.3% – passing gas, every fourth patient (26.3%), sex accompanied with discomfort and pain, 10.5% of patients noted recurrent vulvovaginitis. Most women (75%) had a history of traumatic delivery with perineal tissue damage. The presence of undifferentiated connective tissue dysplasia (NDST) in this group was detected in 18.75% of cases, and its significance in the formation of PPO in reproductive age requires further study.

Read More

UTERINE CAVITY PERFORATION UNDER FAST-TRACK SURGERY CONDITIONS

Posted in 2020, Issue № 07(97) July 2020, MEDICINE | 0 comments

The paper presents the analysis of the results of 599 hysteroscopic operations, which were carried out under fast-track surgery conditions in the day hospital of the Municipal Hospital named after M.P. Konchalovsky, the Department of Health in Moscow. According to the results, a complete perforation of the uterus was found in 0.667% of cases. Based on the comparative analysis and case features, the authors made several recommendations on the measures to reduce these intraoperative complications in fast-track surgery: identify a risk group, completely visualize the process at all stages of hysteroscopic interventions, apply a multidisciplinary approach at the prehospital and inpatient stage of treatment, as well as the principles of conservative treatment of complications.

Read More

CORRELATION OF DEPRESSION AND TYPE 2 DIABETES

Posted in 2020, Issue № 07(97) July 2020, MEDICINE | 0 comments

The authors present topical data on the epidemiology, clinical significance, and pathogenetic relationship of depression and type II diabetes mellitus. They consider basic general pathophysiological links of this connection, including genetic, neuroendocrine, neurobiochemical immuno-inflammatory, as well as psychological aspects of the interdependence of depression and type II diabetes mellitus. The role of risk factors that provoke the risk of developing type II diabetes in the presence of the depressive disorder is discussed as well: the activation of the hypothalamic-pituitary-adrenal axis and sympathoadrenal system, behavioral features, psychopharmacotherapy with antidepressants. Also, the authors describe the risk factors for the development of depression in the presence of type II diabetes: chronic somatic distress, impaired trophism of nervous tissue, elevated levels of cortisol in the blood. They consider data confirming the negative impact of comorbid depressive disorders on the development of chronic complications of type II diabetes, the quality of life of patients. Given the high contingency of these diseases, the following conclusion is made: a comprehensive multidisciplinary approach to the treatment of patients with depression and type II diabetes is required. When taking antidepressants, it is advisable for patients with depressive disorders to control body weight, glucose level, and blood lipid spectrum. In patients with type II diabetes, it is required to screen and treat depressive disorders as part of the mandatory routine care for patients with type II diabetes.

Read More

ECHOCARDIOGRAPHY IN PATIENTS OPERATED DUE TO ISCHEMIC HEART DISEASE (PART II)

Posted in 2020, Issue № 07(97) July 2020, MEDICINE | 0 comments

Diseases of the blood supply system take the leading place among the causes of mortality in Russia, as well as in most developed countries. Ischemic heart disease has a large share in the structure of these pathologies; it is the leading cause of hospitalization, the mortality of the country’s able-bodied population, and is a significant medical and social problem. The high incidence of coronary disease causes the need to increase not only the effectiveness of its diagnosis but also postoperative control. In the first part of the review, the authors have examined the main aspects of transthoracic echocardiography in patients after port-coronary shunt procedures and percutaneous coronary interventions. However, stress echocardiography and transesophageal ultrasound scanning are actively used in addition to standard ultrasound examination of heart in patients with coronary artery disease. In addition to these methods, in echocardiographic laboratories, it is also possible to use intravascular studies of coronary arteries and other additions to transthoracic echocardiography.

Read More

ECHOCARDIOGRAPHY IN PATIENTS OPERATED DUE TO ISCHEMIC HEART DISEASE. TRANSTHORACIC ECHOCARDIOGRAPHY (PART I)

Posted in 2020, Issue № 07(97) July 2020, MEDICINE | 0 comments

Currently, cardiovascular diseases remain the leading cause of morbidity and mortality around the world. The treatment and diagnostic capabilities in helping patients suffering from ischemic heart disease (IHD) improve every year. The main invasive methods for the treatment of ischemic heart disease today include coronary artery bypass grafting and stenting. Interventional treatment of coronary artery disease is successful in most cases, but there are adverse outcomes. One of the leading diagnostic methods for predicting and timely detection of complications, as well as assessing the success of the intervention is the echocardiographic examination of the heart. The first part of this review presents relevant domestic and foreign data on the main modern possibilities of transthoracic echocardiography in patients with coronary artery disease who underwent coronary artery bypass grafting or stenting.

Read More

EXPERIMENTAL JUSTIFICATION OF RESERVE ADAPTIVE CAPABILITIES OF PHYSIOLOGICALLY ATHLETE’S HEART BY TRANSMITRAL FLOW IN QUALIFIED ATHLETES

Posted in 2020, Issue № 07(97) July 2020, MEDICINE | 0 comments

The paper presents the morphometric and hemodynamic parameters of a heart; it presents data from the study of the response of the cardiovascular system to the physical activity of aerobic orientation in subjects from the control and experimental groups. The obtained results allow us to state that in individuals from the experimental group with a reserve of functional capabilities of a heart, the indicators of physical fitness are higher than in individuals in the control group.

Read More

DYNAMICS OF LOCOMOTOR APPARATUS STATE IN CHILDREN AND ADOLESCENTS

Posted in 2020, Issue № 07(97) July 2020, MEDICINE | 0 comments

The relevance of this study is determined by the prevalence of disorders and diseases of the musculoskeletal system (MSS) among children. The paper provides information on the structure of the incidence of MSS in children aged 0 to 18 years, from 2016 to 2019, living in the Dakhadaevsk district. The author analyzed the results obtained from copying the data from the primary medical documentation. The paper presents the statistical data and dynamics of changes in the state of the MSS and reveals unfavorable trends in dynamics. When analyzing the structure of the incidence rate, scoliosis and flat feet are at the leading positions.

Read More

COMPLICATED SUBUNGUAL HEMATOMA: PROSPECTIVE EFFICIENCY STUDY OF VARIOUS OPTIONS OF SURGICAL INTERVENTION

Posted in 2020, Issue № 07(97) July 2020, MEDICINE | 0 comments

The paper is devoted to efficacy evaluation of surgical treatment of complicated subungual hematoma in patients with closed injuries of the phalanx distalis of fingers and toes. This work provides information on the intervention methods for this pathology: partial resection, removal of a nail plate, and onychoperforation operation. The results of the study show that onychoperforation, compared with resection and removal of a nail plate, significantly reduces the likelihood of complications of inflammatory (OR = 4.97 RR = 4.63) and purulent-necrotic (OR = 10.0 RR = 9,25) nature in the immediate postoperative period, and reduces the risks of nail plate curvature in the long term (OR = 7.31 RR = 5.92).

Read More

MAIN ASPECTS OF BIOCHEMISTRY, PHYSIOLOGY OF CARDIAC TROPONINS

Posted in 2020, Issue № 06(96) June 2020, MEDICINE | 0 comments

This review article briefly discusses basic information about the biochemistry and physiology of cardiac troponins. Cardiac troponins (troponin I, T, and C) play an important role in the regulation of contractile function of the heart muscle. Mutations in cardiac troponins are associated with the development of various types of cardiomyopathies, which lead to heart failure and death. The determination of the concentration of cardiac troponins in the blood is used in the diagnosis of some cardiovascular diseases, including acute myocardial infarction, myocarditis, heart failure. This review summarizes the available data on the structure and functions of cardiac troponins, their role in the regulation of myocardial contractions and clinical application.

Read More

EFFICIENCY OF APPLICATION OF EXISTING METHODS FOR FORECASTING SUGGESTED BIRTH DATE AT LOW PERINATAL RISK

Posted in 2020, Issue № 06(96) June 2020, MEDICINE | 0 comments

The currently used methods for predicting the estimated date of delivery (EDD) for uncomplicated single-pregnancy pregnancies of low perinatal risk are characterized by significant differences in the actual and predicted delivery times. The goal of the study is to evaluate the effectiveness of existing methods for predicting the date of delivery. The authors studied 68 episodes of the pregnancy course and childbirth and determined the degree of discrepancy between the predicted and the actual date of independent delivery using the existing methods. Negele method using the first day of the last regular menstruation and the obstetric (28 days) month in the formula, as well as the first fetal ultrasound screening at 11-12 weeks of gestation, were found to be reliable forecasting methods.

Read More