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MEDICINE

ISSN 2227-6017 (ONLINE), ISSN 2303-9868 (PRINT), DOI: 10.18454/IRJ.2227-6017
ЭЛ № ФС 77 - 80772, 16+

INFLUENCE TAGANSORBENT ON ORGANIZM

Posted in 2013, Issue № 9(16) September 2013, MEDICINE | 0 comments

The research project is concerned with examination of the anatomical status of gum epitheliumin response to poisonous action of cadmium chloride and Tagansorbent application.

The goal of the research project is examination of structural organization of animal gum under conditions of chronic intoxication with cadmium chloride and correction with Tagansorbent.

The practical relevance of results of the project consists in the fact that knowledge on the structural organization of a gum within normal range and under chronic intoxication with cadmium chloride, not only made it possible to detect “the malfunction” in the system, but also provided the opportunity to recommend endoecological rehabilitation.

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MIXED-INFECTIONS OF THE SKIN WHERE THE EPIDERMIS IS THIN AND DELICATE TOPICAL COMBINED MEDICATIONS

Posted in 2013, Issue № 9(16) September 2013, MEDICINE | 0 comments

The study population included 40 male and female patients from Russia 22-58 years old. The patients were asked to grade treatments for different manifestations, including mycosis large folds – 28 patients, combined skin diseases where the epidermis is thin (face, ears, scrotum) – 12 patients. Patients were given strong recommendations and treated by themselves during 10-30 days. Assessment of efficiency of the treatment is based on the researcher’s conclusion about the expression of symptoms and opinions of patients about their complaints and changes of investigated manifestations. Finally, it was established bright clinic efficiency and safety of topical combined medication for the treatment mixed-infections of the skin where the epidermis is thin. None of the currently available therapeutic options are ideal, although they provide some relief, but the drug we investigated showed the best results herewith stay the most safety. Thus rightly be considered that the topical combined medication is highly effective and safe, it doesn’t cause suppression of adrenocorticals, and simplex to use.

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HUMAN ENDOGENOUS RETROVIRUS HERV – E λ 4 – 1 IMMUNOTROPIC PROPERTIES UNDER THE INTRAVITAL ESTABLISHING OF ITS ENV REGION PROTEIN TO EXPERIMENTAL ANIMALS

Posted in 2013, Issue № 9(16) September 2013, MEDICINE | 0 comments

Presented data indicate the immunostimulatory properties of the human endogenous class I retrovirus HERV – E λ 4 – 1 on the basis of the influence of a synthetic peptide homologous to the amino acid sequence of env region protein of the retrovirus on the immune system’s organs morphometric parameters as well as the functional activity of immunocompetent cells, in particular, the proliferative potential and the formation of a cellular immune response.

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THE COMPARATIVE CHARACTERISTIC OF α-ADRENERGIC BLOCKERS AT DISTAL URETERAL STONES

Posted in 2013, Issue № 9(16) September 2013, MEDICINE | 0 comments

Comparative research of use of terazosin, doxazosin, and tamsulosin is conducted at stones of distal ureter. It is proved that efficiency α-adrenergic blockers is identical. Absence of arterial hypotension when using tamsulosin is the main criterion defining a choice of α-adrenergic blocker for exile of a stone from an ureter. Results can be used in urological practice.

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REACTIVE CHANGES IN THE MORPHOLOGICAL COMPOSITION OF RAT BLOOD DURING INTRAGASTRIC LOADING WITH AQUEOUS STRAWBERRY EXTRACT

Posted in 2021, Issue №9 (111) September 2021, MEDICINE | 0 comments

The balance of processes in living organisms consists in the equilibrium ratio of the processes of synthesis and decay of free radicals, which are of the most important importance for ensuring the protective reactions of the body, the adaptation of cells to changing environmental conditions. In the case of imbalance of the processes of antioxidant protection of the body, the excessive formation of free radicals leads to functional disorders of a wide range.

It is possible to partially compensate for the lack of protective systems of the body and contribute to the restoration of homeostatic balance by using biologically active substances such as water extract of strawberries, which has antioxidant properties, contributing to the restoration of homeostasis at all levels of the body thus creating sufficient adaptive potential. The aim of the article is to study the reactive changes in the morphological composition of rat blood to intragastric load with an aqueous strawberry extract. The experiment was conducted on 60 white laboratory rats in the amount of 60 pieces. Conclusion: compared to the blood of animals of the control group, intragastric administration of aqueous strawberry extract at a concentration of 15 mg/100 g of animal body weight is expressed by such reactive changes in the morphological composition of blood as an increase in the number of red blood cells (6.8 %), hemoglobin concentration (4.89 %), the number of white blood cells (16.4 %).

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EPIDEMIOLOGICAL ASPECTS OF PEDICULOSIS IN CHILDREN OF ASTRAKHAN OBLAST

Posted in 2021, Issue №9 (111) September 2021, MEDICINE | 0 comments

The aim of the article is to study and analyze the epidemiological state of pediculosis in children of Astrakhan Oblast for the period from 2016 to 2020.

Materials and methods. In Astrakhan Oblast, for the period from 2016 to 2020, 1202553 cases of human infection with infectious and parasitic diseases were registered, out of which parasitic infestations accounted for 1.3% (15348 cases). The share of pediculosis in the structure of all infectious diseases accounted for 0.4%, and in the structure of all parasitic infestations – 34.4% (5274 cases).

The results of the study. As it was noted earlier, during the analyzed period, 5274 cases of pediculosis were registered in the territory of Astrakhan and Astrakhan Oblast, out of which more than half of the cases were children under the age of 17.

Cases of pediculosis in children were observed at the age of 6 months to 17 years. Pediculosis in children aged 6-12 months was registered in 0.4% (14 people). The share of children aged from 1 to 7 years accounted for 19.4% (747 people). Percentage of school-age children (7-17 years old) amounted to 80.2% (3087 people).

Conclusions: as evidenced by the figures shown above, pediculosis in Astrakhan Oblast is registered annually and most often occurrs among children under the age of 17 years. Children of various ages are susceptible to the disease, particularly school-age children (7-17 years old). The registered cases of pediculosis in children aged 6-12 months indicate that the parents do not possess necessary hygienic skills or there is a family source, in which one and/or both parents are sick with pediculosis. The presence of pediculosis in children aged 7-17 years indicates either a large crowding of patients or an epidemic focus in the classroom or school.

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DEFECTS AND ARTIFACTS DETECTED DURING LABORATORY TESTS ON ENVIRONMENTAL SAMPLES

Posted in 2021, Issue №9 (111) September 2021, MEDICINE | 0 comments

The purpose of the studyis to analyze the collected set of micro-preparations prepared during sanitary and parasitological studies on environmental samples.

Materials and methods. The research is carried out on the basis of the Department of Infectious Diseases and Epidemiology of the Astrakhan State Medical University of the Ministry of Health of the Russian Federation and the Department of General and Infectious Pathology of the State Medical Institution of JSC “Pathoanatomic Bureau of Astrakhan” (AO “Patalogoanatomicheskoe byuro goroda Astrakhani) in the period from 2019 to 2020.

Results and discussion. In 2019-2020, a selection of preparations with various artifacts obtained during sanitary and parasitological studies of the environment (water, soil, samples from hard surfaces, studies of fruit and vegetable and fish products) was carried out. The total of the conducted studies conducted by the members of the student research circle of infectious and parasitic diseases of the Astrakhan state medical University amounts to 635 samples selected from various environmental objects, including 152 soil samples (23,9%), 53 water samples (8.3%) of 60 samples from hard surfaces (9,4%), 88 samples of fruits and vegetables (13.9%) and 282 samples of fish and fish products (44,4%). The number of samples that do not meet sanitary and parasitological indicators equaled 4.7%.

At the same time, a collection of artifacts of various micro-preparations was obtained during sanitary and parasitological studies of environmental samples.

Old glass was observed in 31 cases (18%). As a rule, the glass had scratches. In other cases, foreign particles and trace elements as well as the presence of conditionally pathogenic or free-living microorganisms were observed in micro-preparations. All these inclusions might be taken by specialists for eggs or larvae of helminths, which in turn is considered an error of the microscopist.

Conclusions. The collected samples are not able to reflect the large-scale defects and artifacts detected during various laboratory studies conducted by various laboratory units of Astrakhan Oblast, but it can serve as a clear example of preventing the occurrence of the above errors when conducting sanitary and parasitological studies of environmental samples. Defects and artifacts of sanitary and parasitological studies taken by a specialist for the pathogen can negatively affect the issuance of an incorrect sanitary and epidemiological conclusion on the contamination of a particular environmental object with eggs and larvae of helminths as well as cysts of pathogenic intestinal protozoa.

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POST-COVID SYNDROME IN CHILDREN

Posted in 2021, Issue №9 (111) September 2021, MEDICINE | 0 comments

The Alpha variant of COVID-19 has been identified in residents of Yakutia. Having recovered from this variant, the children were observed to have post-covid syndrome. The aim of the study was to study the features of the course of post-covid syndrome in children after infection with the Alpha variant. In total, 500 patients who had SARS-CoV-2 infection were examined in a private clinic. Out of these patients, 100 children had the SARS-CoV-2 infection were observed to have post-covid syndrome. All patients had suffered SARS-CoV-2 infection during the previous 6 months. The age of patients is from 1 to 15 years. Children after COVID-19 had the following clinical manifestations of post-covid syndrome: frequent acute respiratory infections and tonsillitis in the next 6 months, fatigue and weakness, changes in taste and smell, sleep disorders. During the following months, changes in general clinical, biochemical tests and immunograms were noted.

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THE LEVEL OF ADAPTIVE CAPABILITIES OF CARDIOVASCULAR SYSTEM IN ADOLESCENT CADETS

Posted in 2021, Issue №9 (111) September 2021, MEDICINE | 0 comments

Currently, the state of health of schoolchildren causes serious concerns, therefore, the preventive detection of functional disorders and the prevention of the development of diseases is an interesting topic. Assessment of the conditions of training in cadet boarding school educational institutions remains a very urgent task in the educational and medical fields due to the round-the-clock influence of factors of the educational environment on the organism of children. The article features a dynamic study of the endurance indicators of the cardiovascular system of cadets studying in boarding school educational institutions. The conducted research demonstrates positive dynamics and a sufficient level of adaptive reserves of students of the cadet corps. However, indicators reflecting the level of systemic hemodynamics by the end of the academic year demonstrate an increase in the level of tension of the cardiovascular system. The results of the study reflect the need for further in-depth study of the impact of new learning conditions in order to optimize the educational process.

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THE SEVERITY OF UNDIFFERENTIATED CONNECTIVE TISSUE DISEASE AS A RISK FACTOR FOR DEPRESSION IN PATIENTS WITH ACUTE CORONARY SYNDROME

Posted in 2021, Issue №9 (111) September 2021, MEDICINE | 0 comments

To study the incidence of depression and to assess the severity of undifferentiated connective tissue disease as a risk factor for depression in patients with acute coronary syndrome (ACS) against the background of undifferentiated connective tissue disease, the study involved 241 patients aged 35 to 65 years who were admitted for inpatient treatment at the State Medical Institution of S. M. Kirov State Clinical Hospital No. 3 and at the Regional Vascular Center of the Alexandro-Mariinskyregional Clinic Hospital in the period from 2018 to 2019. The first group of subjects included 113 patients diagnosed with ACS in combination with undifferentiated connective tissue disease, the second group included 128 patients with ACS without this syndrome. There was an association of an increase in the frequency of occurrence of patients with depression at grade 3 of UCTD, both in the group of patients with UCTD without ACS, and more pronounced in ACS against the background of UCTD, which was confirmed by an increase in the frequency of depression in subgroups of patients with grade 3 of UCTD, an increase in absolute and relative risk, the ratio of chances of depression in subgroups of patients with grade 3 of UCTD with ACS against the background of UCTD compared with subgroups of patients with UCTD without ACS. The study concludes that both the second and, to a greater extent, the third degree of severity of UCTD acts as a risk factor for the development of depression in UCTD both in cases of one single disease and in patients with ACS on the background of UCTD.

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A COMPARATIVE ANALYSIS OF THE TREATMENT OF PATIENTS WITH PERFORATED GASTRIC AND DUODENAL ULCERS

Posted in 2021, Issue №9 (111) September 2021, MEDICINE | 0 comments

The article presents a comparative analysis of the treatment of patients with a perforated form of peptic ulcer disease of the stomach and duodenum on the basis of the State Clinical Hospital No. 8. g of Ufa for the period from 2009 to 2012. All patients were divided into two groups: the first group – females, the second — males. The number of patients in the first group was 21 (14.4%), the average age was 49.8 years. The number of patients in the second group was 124 (85.5%) with the average age of 37.9 years. In the diagnosis of this pathology, such methods as fibroesophagogastroduodenoscopy (EGD – 66.8%), overview radiography of the abdominal cavity (57.2%) and ultrasound examination of the abdominal cavity (abdominal ultrasonography – 47.5%) were used. In the course of the disease, there is an increase in the incidence of peptic ulcer disease among women, while in the second group (male), the incidence decreases. Complications in the early postoperative period were observed only in the second group. However, as for the postoperative mortality, in the first group it was observed to be higher (14.2%).

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CLINICAL SITUATIONS OF DELAYED GROWTH IN CHILDREN IN THE ACTIVITY OF A DISTRICT PEDIATRICIAN

Posted in 2021, Issue №9 (111) September 2021, MEDICINE | 0 comments

The article presents an analysis of clinical cases when the main complaint of the patient is delayed growth. The authors examines the urgency of the problem and the situation of the variety of causes of delayed growth in children. It is shown that it is important for the district pediatrician to remember that a delay in physical development can be an early manifestation of serious endocrinological, genetic, nephrological, cardiological and other diseases. The article also features materials from original observations. It is shown that most often it is enough to collect anamnesis in detail, correctly interpret the indicators of objective examination, including physical development, prescribe general clinical tests in order to timely suspect a serious disease and assign the necessary amount of examination.

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EPIDEMIOLOGICAL CHARACTERISTICS OF THE INCIDENCE OF PATIENTS WITH PEDICULOSIS

Posted in 2021, Issue №9 (111) September 2021, MEDICINE | 0 comments

Stable registration of pediculosis among the population confirms the urgency of the problem. The rise in the incidence of pediculosis is facilitated by frequent reinfection associated with the lack of proper timely and simultaneous treatment of sources in families and groups, insufficient awareness of adults about pediculosis and self-medication.

The aim of the studyis the epidemiological characteristics of the incidence of pediculosis in the population.

Research objectivesare

to conduct a retrospective analysis of the incidence of pediculosis in patients who applied to skin and venereological dispensary in the period from 2010 to 2019.;
to conduct a retrospective analysis of the incidence of head pediculosis in patients who applied to a skin and venereological early treatment and prevention center in 2019.

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CHANGES IN THE CONTENT OF ADRENOCORTICOTROPIC HORMONE AND CORTISOL IN SAILORS DURING A VOYAGE TO VARIOUS CLIMATIC AND GEOGRAPHIC REGIONS

Posted in 2021, Issue №9 (111) September 2021, MEDICINE | 0 comments

The labor activity of seafarers is associated with difficult conditions and requires a high degree of adaptation of the regulatory systems of the body. The endocrine system (especially the pituitary-adrenal axis) is one of the key ones in ensuring adaptation. The nature of changes in hormonal secretion determines the ability of the body to survive and comfortable existence. The purpose of the study is to examine the changes in hormonal parameters in sailors during the voyage to various climatic and geographic regions. Materials and methods. Russian sailors were examined in the dynamics of the voyage to various climatic and geographic regions, in which the content of adrenocorticotropic hormone (ACTH) and cortisol was determined four times (before, at the beginning, in the middle and at the end of voyage). Results and discussion. At the beginning of the voyage, the level of ACTH and cortisol increases; by the middle of the flight, ACTH decreases, and cortisol remains at the same values; by the end of the flight, the levels of both hormones decrease and reach values much lower than before the voyage. The first half of the hormone dynamics indicates the normal course of the general adaptation process, but a further decrease in ACTH and cortisol levels may be a predict a breakdown of adaptive potential.

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AN ANALYSIS OF GUNSHOT WOUNDS ACCORDING TO THE FORENSIC MEDICAL EXAMINATION IN ASTRAKHAN OBLAST FOR THE PERIOD FROM 2006 TO 2020

Posted in 2021, Issue №9 (111) September 2021, MEDICINE | 0 comments

Forensic medical examination of gunshot wounds is a very complex process. In the structure of violent death, gunshot wounds occupy the smallest percentage at this time, but they are socially significant. The article examines the epidemiological characteristics of gunshot wounds according to the forensic medical examination in Astrakhan Oblast for the period from 2006 and up to 2020. The study identifies a decrease in the number of victims of gunshot wounds in Astrakhan Oblast, which is relevant in peacetime and increases the efficiency, quality and evidence of forensic medical examinations.

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PERSONALIZED APPROACH AND ASSESSMENT OF ALGIC STATUS IN CHRONIC PELVIC PAIN SYNDROME

Posted in 2021, Issue №9 (111) September 2021, MEDICINE | 0 comments

Chronic pelvic pain is a socially significant medical problem since chronic pain syndrome adversely affects the psychological state of patients, their ability to work and function in family and society. Chronic pelvic pain is a multidisciplinary problem since it can occur due to various diseases. The review examines the main criteria for an objective assessment of chronic pelvic pain with the introduction of scales for a personalized approach to the diagnosis of algic status. The article also features pharmacological and non-pharmacological methods of helping patients suffering from chronic pelvic pain. The presented information will help clinicians of any specialty in assessing pain syndrome and in determining treatment tactics.

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DIAGNOSIS OF MYOCARDITIS IN THE CONTEXT OF THE COVID-19 PANDEMIC

Posted in 2021, Issue №9 (111) September 2021, MEDICINE | 0 comments

Since December 2019, the new COVID-19 infection has led to significant morbidity and mortality worldwide. However, the information on heart damage in patients affected by COVID-19 is limited. The study establishes that myocardial damage has a significant association with the fatal outcome from COVID-19, while the prognosis for patients with a major cardiovascular disease but without myocardial damage was relatively favorable.

The authors of the article demonstrate the occurrence of cardiac arrhythmias at the outpatient stage. Given that arrhythmias are one of the clinical manifestations of myocarditis, the authors speculate on the possibility of increasing the incidence of viral myocarditis in patients presenting to the cardiologist with cardiac arrhythmias in the context of COVID-19 and propose using magnetic resonance imaging of the heart with contrast enhancement with gadolinium for the timely diagnosis of myocarditis in patients with frequent ventricular and supraventricular extrasystole.

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THE USE OF BACTERIOPHAGES IN CHRONIC TONSILLITIS

Posted in 2021, Issue №9 (111) September 2021, MEDICINE | 0 comments

Currently, the widespread use of antibacterial drugs and their uncontrolled intake have led to selection among pathogenic microflora and the formation of persistent resistance to these methods of treatment due to changes in the genome of microorganisms. Despite the development of medical technologies and methodologies, including the field of otorhinolaryngology, the issue of treatment of patients with chronic tonsillitis remains relevant. The use of bacteriophage preparations stimulates the activation of specific and non-specific immunity factors, therefore phage therapy is especially effective in the treatment of chronic inflammatory diseases of the pharynx of bacterial etiology, including children.

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ORGANIZATION OF SUMMER RECREATION FOR CHILDREN AND ADOLESCENTS IN ASTRAKHAN OBLAST

Posted in 2021, Issue №9 (111) September 2021, MEDICINE | 0 comments

The current article examines the influence of short-term rest and the effectiveness of recovery on the somatometric and physiometric indicators of children. In total, the study involved 149 people aged 7-15 years who were on vacation in a recreational children’s camp. For a comprehensive assessment of the effectiveness of improving the health of children in the camp on the first and second day of the season, as well as on the twentieth day, a medical examination of all vacationers was conducted using various research methods. According to the results of the study conducted at the beginning and at the end of the season, the total effectiveness of recovery is pronounced health effect – 135 (90.8%), weak health effect – 14 (9.2%), no health effect – 0%. Therefore, the study of improving the health of children in relation to environmental factors makes it possible to increase the effectiveness of measures aimed at improving the quality of the environment and the health of the younger generation.

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ON THE THE RELEVANCE OF TEACHING THE “FUNDAMENTALS OF MODERN MEDICAL TECHNOLOGIES” COURSE AT THE HIGHER LEVEL OF PROFESSIONAL EDUCATION

Posted in 2021, Issue №8 (110) August 2021, MEDICINE | 0 comments

From the point of view of the qualitative formation of professional competencies of medical specialists, the current article highlights the relevance of teaching the “Fundamentals of modern medical technologies” course at the highest level of professional education. The authors of the article examine the concept of “technology”, interpret medical technology as the basis of any medical intervention, foreground the problem of “distinguishing ” high-tech and other (traditional) types of medical care from the point of view of the technologies used, give a number of examples of regulating the technologies used in medicine, and conclude that it is advisable to teach the basics of modern medical technologies at the highest level of professional education.

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